タバルマブ（遺伝子組換え) Tabalumab

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Tabalumab

タバルマブ（遺伝子組換え)
Tabalumab (Genetical Recombination)
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[1143503-67-6]

Tabalumab (LY 2127399) is an anti-B-cell activating factor (BAFF) human monoclonal antibody designed for the treatment of autoimmune diseases and B cell malignancies.^[1][2] Tabalumab was developed by Eli Lilly and Company.

A phase III clinical trial for rheumatoid arthritis was halted in Feb 2013.^[3] In September 2014, a second phase III trial focussing on treating systemic lupus erythematosus, was terminated early as the study failed to meet its primary endpoint.^[4]

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References

• 1 “Statement On A Nonproprietary Name Adopted By The USAN Council: Tabalumab” (PDF). American Medical Association.
• 2 http://www.lillyoncologypipeline.com/Pages/baff-antibody.aspx
• 3http://lilly.mediaroom.com/index.php?s=9042&item=136985
• 4http://www.genengnews.com/gen-news-highlights/lilly-halts-tabalumab-development-for-lupus/81250423/

abalumab

Monoclonal antibody
Type	Whole antibody
Source	Human
Target	BAFF
Identifiers
CAS Number	1143503-67-6 Image may be NSFW. Clik here to view.
ATC code	none
ChemSpider	none
Chemical data
Formula	C6518H10008N1724O2032S38
Molar mass	146.25 kg/mol

////////////タバルマブ ,  遺伝子組換え, Tabalumab, 1143503-67-6, antibody, Monoclonal antibody

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