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Single molecule fights heart disease on two fronts
1-Fe Could antioxidant that also inhibits cholesterol biosynthesis be more effective than statins? Researchers in Israel have identified an antioxidant that can lower cholesterol levels as well as...
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Study shows flavonoid Luteolin can block cancer cell signaling
Luteolin, a flavonoid compound commonly found in fruit and vegetables, has been found to be able to surppress the activity of cell signaling pathways (IGF and PI3K) that play key roles in growth of...
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Semisynthetic Latrunculin Derivatives as Inhibitors of Metastatic Breast...
The microfilament cytoskeleton protein actin plays an important role in cell biology and affects cytokinesis, morphogenesis, and cell migration. These functions usually fail and become abnormal in...
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Experimental Drug Shows Promise for Rare Genetic Disorder
Transthyretin, or TTR for amyloidosis THURSDAY Aug. 29, 2013 — A new medication appears to be highly effective in combating a heredity-based form of the organ-damaging genetic disorder known as...
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Cyclic Dinucleotide Senses HIV
The enzyme cyclic GMP-AMP synthase stimulates the immune response during HIV infections Read more http://www.chemistryviews.org/details/news/5109171/Cyclic_Dinucleotide_Senses_HIV.html
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Bladder Cancer Drug Pipeline Update 2013
Bladder Cancer Drug Pipeline Update 2013 Sacramento Bee Pipeline Breakdown According to Number of Drugs Marketed# 10 Pre-registration# 1 Phase III# 4 Phase II# 45 Phase I# 26 Preclinical# 29...
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Turmeric Extract 100% Effective At Preventing Type 2 Diabetes, ADA Journal...
A remarkable human clinical study published in the journal Diabetes Care, the journal of the American Diabetes Association, revealed that turmeric extract was 100% successful at preventing prediabetic...
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DCGI asks Wockhardt, Ranbaxy to explain lapses
Indian drug makers Ranbaxy and Wockhardt have been issued a letter by the DCGI to explain deficiencies found at the company’s manufacturing units Following an import alert by the US FDA, Indian drug...
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Oramed Submits Pre-IND Package to FDA for ORMD-0901 (oral exenatide)
Oramed Submits Pre-IND Package to FDA for ORMD-0901 (oral exenatide), an … MarketWatch JERUSALEM, September 3, 2013 /PRNewswire via COMTEX/ — Oramed Pharmaceuticals Inc. (nasdaqcm:ORMP)...
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This Biotech Has So Many Reasons to Be Liked
This Biotech Has So Many Reasons to Be Liked Motley Fool With promising mid-stage results, the drug is expected to do well in phase 3 evaluation for pancreatic cancer. Positive phase 3 results will...
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Mallinckrodt PLC : Mallinckrodt Pharmaceuticals Announces Positive Phase 3...
MALLINCKRODT PLC : Mallinckrodt Pharmaceuticals Announces Positive … 4-traders (press release) Mallinckrodt (NYSE: MNK) today reported data that investigational drug MNK-795 achieved the primary...
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“PROSTAGLANDIN” A USEFUL STRATEGY FOR NEW DRUG DEVELOPMENT: A REVIEW
ABSTRACT: The prostaglandins are a family of lipids, originally discovered over 30 years ago in human seminal fluid, which have since been found not only to have a wide variety of striking...
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Melatonin: It’s Not Just for Bedtime Anymore – Part 1
Melatonin is a neurohormone that is produced in the brain, primarily by the pineal gland, from the amino acid tryptophan. Its most well known functions include helping to regulate sleep and the body’s...
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Comparing China’s And India’s Pharmaceutical Manufacturing
By Jim Zhang, Ph.D., JZMed, Inc. The pharmaceutical markets of China and India have been experiencing such rapid growth in the past decade that they are widely recognized as two of the world’s most...
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Drug in Focus: Abiraterone Acetate (Zytiga) New drug for the treatment of...
Abiraterone Acetate (Zytiga) When prostate cancer spreads to another location in the body, it is considered to have metastasised, and surgery to remove the prostate and pelvic lymph nodes cannot...
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AstraZeneca pays $50 million upfront for Merck & Co cancer drug
AstraZeneca has licensed a drug which is in mid-stage studies for ovarian cancer from Merck & Co. The pact centres around the US drug major’s MK-1775, an oral small molecule inhibitor of WEE1...
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ESCITALOPRAM
128196-01-0 ESCITALOPRAM Escitalopram (also known under various trade names) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is approved by the U.S. Food and Drug...
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The strategy of enantiomer patents of drugs
The strategy of enantiomer patents of drugs Drug Discovery Today, Volume 15, Issues 5–6, March 2010, Pages 163-170 http://www.sciencedirect.com/science/article/pii/S1359644610000310 Israel Agranat...
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LEVOCETRIZINE
LEVOCETRIZINE Levocetirizine (as levocetirizine dihydrochloride) is a third-generation non-sedative antihistamine, developed from the second-generation antihistamine cetirizine. Chemically,...
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Novartis’ Breakthrough Therapy For A Rare Muscle-Wasting Disease
On August 20, 2013, Novartis announced in a press release that the FDA had granted breakthrough therapy designation to its experimental agent BYM338 (bimagrumab) for treatment of the rare muscle...
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