Risk Assessment of Potentially Genotoxic Impurities within the Framework of...
A strategy for the risk assessment of potentially genotoxic impurities is described that utilizes Quality by Design in an effort to furnish greater process and analytical understanding, ultimately...
View ArticleHow to Handle Drug Polymorphs… Case Study of Trelagliptin Succinate
Pharmaceutical API Polymorphs… case study of Trelagliptin CASE STUDY WITH..Compound I having the formula WO2008067465A1 OR US8084605 IS THE PATENT USED AND WITH FORM “A” AND AMORPHOUS FORM Active...
View ArticleFONDAPARINUX
FONDAPARINUX Fondaparinux is a drug belonging to the group of the antithrombotic agents and are used to prevent deep vein thrombosis in patients undergoing orthopedic surgery. It is also used for the...
View ArticleCAPREOMYCIN
Structure Capreomycin is a peptide antibiotic, commonly grouped with the aminoglycosides, which is given in combination with other antibiotics for MDR-tuberculosis. Adverse effects include...
View ArticleILOPERIDONE
Iloperidone (Fanapt), ILO-522, HP-873, Zomaril, 133454-47-4, antipsychotic 1-[4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]ethanone;...
View ArticleTemozolomide 替莫唑胺
Temozolomide 替莫唑胺 Temozolomide is a DNA damage inducer. 4-methyl-5-oxo-2,3,4,6,8-pentazabicyclo[4.3.0]nona-2,7,9-triene-9-carboxamide...
View ArticleTADALAFIL.. cialis
Tadalafil GF-196960, IC-351, Cialis 6R-trans)-6-(1,3-benzodioxol-5-yl)- 2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino [1', 2':1,6] pyrido[3,4-b]indole-1,4-dione...
View ArticleThe US FDA has issued full approval for Israeli drugmaker Teva’s Synribo...
Omacetaxine mepesuccinate 高三尖杉酯碱 Alkaloid from Cephalotaxus harringtonia; FDA approved orphan drug status for Ceflatonin in the treatment of chronic myeloid leukemia due to being an inducer of...
View ArticleCidofovirסידופוביר سيدوفوفير
CIDOFOVIR (S)-1-(3-Hydroxy-2-phosphonylmethoxypropyl)cytosine [(S)-2-(4-Amino-2-oxo-1,2-dihydropyrimidin-2-yl)-1-(hydroxymethyl)ethoxymethyl]phosphonic acid 113852-37-2 CAS 120362-37-0 (Na salt)...
View ArticlePimecrolimus Пимекролимус…For treatment of mild to moderate atopic dermatitis.
Pimecrolimus 137071-32-0 cas (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)- 3-{(E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]- 1-methylvinyl}-8-ethyl-5,6,8,11,12,13,14,15,16,17,...
View ArticleRUXOLITINIB…FOR THE TREATMENT OF INT OR HIGH-RISK MYELOFIBROSIS
Ruxolitinib (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile, cas no 941678-49-5...
View ArticleOctreotide اکترئتید For treatment of acromegaly and reduction of side effects...
Octreotide (D)-Phe-Cys-Phe-(D)-Trp-Lys-Thr-Cys-Thr-ol....
View ArticleNano drugs..Powder dispersion
Powder dispersion One of the main criteria for the effective drug delivery via lungs is the size of the inhaled particle. Respirable size i.e. the particle is transported to deep lungs (alveoli...
View ArticleCHEMDRAW PRO 8.0
CHEMDRAW PRO 8.0 ChemDraw is a leading chemistry molecules drawing software. ChemDraw is easy to use and best software for drawing a molecule structures and finding stereochemistry of the molecules....
View ArticleLESINURAD
Lesinurad Acetic acid, 2-[[5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-, sodium salt (1:1) Sodium 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-...
View ArticleMIFEPRISTONE
Mifepristone Abortifacient. CAS: 84371-65-3 (11b,17b)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one 17β-hydroxy-11β-(4-dimethylaminophenyl)-17α (Propa-1 ,2-dienyl)...
View ArticleCARBAZITAXEL
Cabazitaxel For treatment of patients with hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen....
View ArticleBERAPROST….Stable prostacyclin analog.
BERAPROST https://www.ama-assn.org/resources/doc/usan/beraprost.pdf 2,3,3a,8b-tetrahydro-2-hydroxy-1-(3-hydroxy-4-methyl-1-octen-6-ynyl)-1H-cyclopenta(b)benzofuran-5-butanoic acid...
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