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Risk Assessment of Potentially Genotoxic Impurities within the Framework of...

  A strategy for the risk assessment of potentially genotoxic impurities is described that utilizes Quality by Design in an effort to furnish greater process and analytical understanding, ultimately...

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How to Handle Drug Polymorphs… Case Study of Trelagliptin Succinate

Pharmaceutical API Polymorphs… case study of Trelagliptin CASE STUDY WITH..Compound I having the formula WO2008067465A1 OR US8084605  IS THE PATENT USED AND WITH FORM “A” AND AMORPHOUS FORM Active...

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FONDAPARINUX

FONDAPARINUX Fondaparinux is a drug belonging to the group of the antithrombotic agents and are used to prevent deep vein thrombosis in patients undergoing orthopedic surgery. It is also used for the...

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IDRAPARINUX… Sanofi (PHASE III)

IDRAPARINUX Nonasodium...

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CAPREOMYCIN

Structure  Capreomycin is a peptide antibiotic, commonly grouped with the aminoglycosides, which is given in combination with other antibiotics for MDR-tuberculosis. Adverse effects include...

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ILOPERIDONE

Iloperidone (Fanapt), ILO-522, HP-873, Zomaril, 133454-47-4, antipsychotic 1-[4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]ethanone;...

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Temozolomide 替莫唑胺

Temozolomide 替莫唑胺 Temozolomide is a DNA damage inducer. 4-methyl-5-oxo-2,3,4,6,8-pentazabicyclo[4.3.0]nona-2,7,9-triene-9-carboxamide...

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TADALAFIL.. cialis

Tadalafil GF-196960, IC-351, Cialis 6R-trans)-6-(1,3-benzodioxol-5-yl)- 2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino [1', 2':1,6] pyrido[3,4-b]indole-1,4-dione...

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The US FDA has issued full approval for Israeli drugmaker Teva’s Synribo...

Omacetaxine mepesuccinate 高三尖杉酯碱 Alkaloid from Cephalotaxus harringtonia; FDA approved orphan drug status for Ceflatonin in the treatment of chronic myeloid leukemia due to being an inducer of...

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Cidofovirסידופוביר سيدوفوفير

CIDOFOVIR (S)-1-(3-Hydroxy-2-phosphonylmethoxypropyl)cytosine [(S)-2-(4-Amino-2-oxo-1,2-dihydropyrimidin-2-yl)-1-(hydroxymethyl)ethoxymethyl]phosphonic acid 113852-37-2 CAS 120362-37-0 (Na salt)...

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RIDAFOROLIMUS

Ridaforolimus 572924-54-0...

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Pimecrolimus Пимекролимус…For treatment of mild to moderate atopic dermatitis.

Pimecrolimus 137071-32-0 cas  (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)- 3-{(E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]- 1-methylvinyl}-8-ethyl-5,6,8,11,12,13,14,15,16,17,...

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RUXOLITINIB…FOR THE TREATMENT OF INT OR HIGH-RISK MYELOFIBROSIS

Ruxolitinib (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile, cas no 941678-49-5...

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Octreotide اکترئتید For treatment of acromegaly and reduction of side effects...

Octreotide (D)-Phe-Cys-Phe-(D)-Trp-Lys-Thr-Cys-Thr-ol....

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Nano drugs..Powder dispersion

  Powder dispersion One of the main criteria for the effective drug delivery via lungs is the size of the inhaled particle. Respirable size i.e. the particle is transported to deep lungs (alveoli...

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CHEMDRAW PRO 8.0

CHEMDRAW PRO 8.0   ChemDraw is a leading chemistry molecules drawing software. ChemDraw is easy to use and best software for drawing a molecule structures and finding stereochemistry of the molecules....

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LESINURAD

Lesinurad Acetic acid, 2-[[5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-, sodium salt (1:1) Sodium 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-...

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MIFEPRISTONE

Mifepristone Abortifacient. CAS: 84371-65-3 (11b,17b)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one 17β-hydroxy-11β-(4-dimethylaminophenyl)-17α (Propa-1 ,2-dienyl)...

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CARBAZITAXEL

Cabazitaxel For treatment of patients with hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen....

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BERAPROST….Stable prostacyclin analog.

BERAPROST https://www.ama-assn.org/resources/doc/usan/beraprost.pdf 2,3,3a,8b-tetrahydro-2-hydroxy-1-(3-hydroxy-4-methyl-1-octen-6-ynyl)-1H-cyclopenta(b)benzofuran-5-butanoic acid...

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