Clik here to view.
p-Anisaldehyde, or 4-methoxybenzaldehyde. NMR
p-anisaldehyde, or 4-methoxybenzaldehyde. (C8H8O2) This 13C spectrum exhibits resonances at the following chemical shifts, and with the multiplicity indicated: Shift (ppm) 190.8 130.2 154.6 114.5...
View ArticleClik here to view.
Ethyl 3-oxohexanoate エチル=3-オキソヘキサノアテ NMR
Ethyl 3-oxohexanoate Cas Number: 3249-68-1 Formula: C8H14O3 The Journal of Organic Chemistry, 44, p. 310, 1979 DOI: 10.1021/jo01316a039 C8H14O3 Rule 2, omit O, gives C8H14 8 – 14/2 + 1 = 2 degrees...
View ArticleClik here to view.
CHMP recommends Teva’s pregnancy prevention drug
The European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) has issued a positive opinion recommending the marketing authorisation of Teva Pharmaceutical’s Seasonique...
View ArticleClik here to view.
GSK and Theravance announce Japanese approval for Anoro Ellipta
GlaxoSmithKline (GSK) and Theravance have obtained approval from the Japanese Ministry of Health, Labour and Welfare for Anoro Ellipta to treat chronic obstructive pulmonary disease (COPD). The...
View ArticleClik here to view.
Mitsubishi Tanabe Pharma Corp. and Daiichi Sankyo Co. Ltd., announced that...
NEWS Diabetes Drug Receives MMA in Japan Mitsubishi Tanabe Pharma Corp. and Daiichi Sankyo Co. Ltd., announced that Mitsubishi Tanabe Pharma has received approval to manufacture and market the...
View ArticleClik here to view.
China struggles to speed up drug reviews
China wants to prioritise new drugs and certain generics over more routine requests © Shutterstock http://www.rsc.org/chemistryworld/2014/07/china-struggles-speed-drug-reviews In an effort to...
View ArticleClik here to view.
Examples of 1H NMR Spectra
These several pages contain some 1H nmr spectra , with annotations and comments. Try to understand why each spectrum looks as it does, including the approximate chemical shifts and the splitting...
View ArticleClik here to view.
Top 10 Pharma – products in the pipeline
Top 10 Pharma – products in the pipeline READ AT http://latampharmara.com/2013/12/15/top-10-pharma-products-on-the-pipeline/ CLICK LINK ABOVE THANKS AND REGARD’S DR ANTHONY MELVIN...
View ArticleClik here to view.
Market Opportunities Report on Poorly Soluble and Poorly Permeable Drugs
Published on July 14, 2014 at 6:04 AM IN AZANO Poor bioavailability is a major reason for compounds to fail in preclinical development. Technology Catalysts International (TCI), a leading global...
View ArticleClik here to view.
How to design drugs that could target particular nerve cells?
The future of drug design lies in developing therapies that can target specific cellular processes without causing adverse reactions in other areas of the nervous system. Scientists at the...
View ArticleClik here to view.
Anthony crasto’s blog New drug approvals touches 3 lakh views…….Helping millions
link is http://newdrugapprovals.org/ All about Drugs, live, by DR ANTHONY MELVIN CRASTO, Worlddrugtracker, Helping millions, 7 million hits on google, pushing boundaries, one lakh plus connections...
View ArticleClik here to view.
Structural and physicochemical aspects of hydrochlorothiazide co-crystals
Structural and physicochemical aspects of hydrochlorothiazide co-crystals CrystEngComm, 2014, 16,6996-7003 DOI: 10.1039/C4CE00666F, Paper Jian-Rong Wang,a Chanjuan Yea and Xuefeng Mei*a *...
View ArticleClik here to view.
DRUG SYNTHESIS USING SUZUKI RXN..Imidazolium ionic liquid-tagged palladium...
Imidazolium ionic liquid-tagged palladium complex: an efficient catalyst for the Heck and Suzuki reactions in aqueous media Green Chem., 2014, Advance Article DOI: 10.1039/C4GC00525B, Paper Pankaj...
View ArticleClik here to view.
Examples of 13C NMR Spectra
No one will present better……….. Examples 13C NMR Spectra Here are a couple of examples for judging 13C chemical shifts: Minimum description used……..mostly pictorial Start with benzene Then toluene...
View ArticleClik here to view.
The $300,000 Drug
Kalydeco is truly a wonder drug. Developed by Vertex Pharmaceuticals, it is the first drug that attacks not just the symptoms but the underlying cause of cystic fibrosis, a genetic lung disease that...
View ArticleClik here to view.
Identification and synthesis of a male-produced pheromone for the neotropical...
1= methyl (E)-3-(2-hydroxyethyl)-4-methyl-2-pentenoate+methyl (E)-3-(2-hydroxyethyl)-4-methyl-2-pentenoate 2= http://www.google.com/patents/US20130189222?cl=en an unsaturated hydroxy ester pheromone...
View ArticleClik here to view.
REDUCTION OF C=O GROUP
- the reduction of carbonyl compounds is one of the most important synthetic reactions - the catalytic enantioselective reduction of C=O has been achieved using: * chiral oxazaborolidines and other...
View ArticleClik here to view.
‘Green’ Route To Chromanols
An enantioselective oxidative reaction produces optically active chromanols, which can then be made into tocopherols and related compounds. read at...
View ArticleClik here to view.
The three key days of immunodeficiency virus
Structure of simian virus very similar to human. / SUPERSTOCK / AGE FOTOSTOCK Three days is what it takes for the virus simian immunodeficiency (SIV), the most similar to HIV, to reach reservoirs...
View ArticleClik here to view.
1-PENTANAL NMR
Formula: C5H10O C5H10O Rule 2, omit O, gives C5H10 5 – 10/2 + 1 = 1 degree of unsaturation. Look for 1 pi bond or aliphatic ring. The band at 1727 indicates a carbonyl, probably an aldehyde; an...
View Article