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Integration in NMR
Place your arrow on above structure of Ethyl acetate………………It will flash see label A,B,C Integration in NMR The intensity of the signal is proportional to the number of hydrogens that make the signal....
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WET GRANULATION
Granulation is the act or process of forming or crystallizing into grains.[1] Granules typically have a size range between 0.2 to 4.0 mm depending on their subsequent use. Synonym “Agglomeration”:...
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FDA Approves Ryanodex for the Treatment of Malignant Hyperthermia
Dantrolene sodium 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-2,4-imidazolidinedione FDA Approves Ryanodex for the Treatment of Malignant Hyperthermia WOODCLIFF LAKE, N.J.(BUSINESS WIRE) July...
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ETHYL PROPIONATE NMR, carbonyl is dad and oxygen mom, a methyl gets more...
Dedicated to all moms C=O group is dad O atom is mom Carbonyl is dad and oxygen mom hence c labelled methyl has higher chemical shift and gets a little more attention SEE BELOW NMR IS EASY A...
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3-BUTYL PYRIDINE, A simple nmr example
3 Butyl pyridine Formula: C9H13N, 135.2062 IR IH NMR SEE http://www.sigmaaldrich.com/spectra/fnmr/FNMR006274.PDF Unsaturation answer C9H13N Rule 3, omit the N and one H, gives C9H12 9 – 12/2 +...
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4-Ethoxybenzaldehyde NMR
Example C9H10O2 MW 150 Calculate the degree of unsaturation: the answer is 5. If the degree of unsaturation is 4 or greater, look for an aromatic ring, which has a degree of unsaturation of 4 (3...
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4-methoxycinnamaldehyde spectral data for learners
4-Methoxycinnamaldehyde C10H10O2 NMR Solvent: CDCl3 Note(s): In the 13C NMR Spectrum, there are two nearly overlapping signals near 127 ppm which are indistinguishable at the initial magnification...
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ROFECOXIB
ROFECOXIB MK-966, MK-0966, Vioxx 162011-90-7 C17-H14-O4-S 314.3596 Rofecoxib /ˌrɒfɨˈkɒksɪb/ is a nonsteroidal anti-inflammatory drug (NSAID) that has now been withdrawn over safety concerns. It was...
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Cystic Fibrosis Letdown Explained Drug Combo: Cell studies suggest way to...
Combination therapies are a promising strategy for correcting the most common gene mutation responsible for cystic fibrosis. A “corrector” drug rescues a misfolded ion channel (purple squiggle) and...
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Scientists Find Sniffing Rosemary Can Increase Memory By 75%
Rosemary is a wonderful herb with a tradition of use spanning millennia. It has innumerable uses in both the kitchen and in herbal medicine. read at...
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Key steps in implementation of QbD for a biotech product…….Quality by design...
Identifying target product profile (TPP). TPP has been defined as a “prospective and dynamic summary of the quality characteristics of a drug product that ideally will be achieved to ensure that...
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Cefuroxime Axetil
Cefuroxime Axetil [6R- [6alpha, 7beta (Z)]] – 3 – [[(Aminocarbonyl) oxy] methyl] -7 – [[2-furanyl (methoxyimino) acetyl] amino] -8-oxo-5-thia-1- azabicyclo [4.2.0] oct-2-ene-2-carboxylic acid 1-...
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Why India is becoming a preferable place for foreign companies to run a...
Why India is becoming a preferable place for foreign companies to run a pharma franchise? Various pharma companies in abroad are looking for partners in India for their pharma franchise business....
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Microsponges: A novel strategy for drug delivery system
Microsponges are polymeric delivery systems composed of porous microspheres. They are tiny sponge-like spherical particles with a large porous surface. Moreover, they may enhance stability, reduce...
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Catalyst-free sulfonylation of activated alkenes for highly efficient...
Catalyst-free sulfonylation of activated alkenes for highly efficient synthesis of mono-substituted ethyl sulfones in water Green Chem., 2014, Advance Article DOI: 10.1039/C4GC00932K, Communication Yu...
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FDA approves first non-invasive DNA screening test for colorectal cancer
August 11, 2014 http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/MedicalDevices/MedicalDevicesAdvisoryCommittee/MolecularandClinicalGeneticsPanel/UCM390229.pdf The U.S. Food...
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European Medicines Agency …Clinical trials in human medicines
The European Medicines Agency relies on the results of clinical trials carried out by pharmaceutical companies to reach its opinions on the authorisation of medicines. Although the authorisation of...
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Aesculus … Hippocastani semen/cortex Aesculus hippocastanum L. Horse-Chestnut...
Aesculus Aesculus hippocastanum The genus Aesculus (/ˈɛskjʊləs/[1] or /ˈaɪskjʊləs/) comprises 13–19 species of trees and shrubs native to the temperate Northern Hemisphere, with 6 species native to...
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Cortendo AB: First Patient Enrolled into NormoCort Phase 3 SONICS Trial...
KETOCONAZOLE 2S 4R ALSO 142128-57-2 228850-16-6 (tartrate) (-)-cis-1-Acetyl-4-[4-[2(S)-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4(R)-ylmethoxy]phenyl]piperazine 531.431, C26 H28...
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Pantoprazole sodium
Protonix; Pantoprazolum; Pantoprazol; Pantozol; 102625-70-7; Pantoprazole Sodium; BY-1023; Pantoloc Molecular Formula: C16H15F2N3O4S Molecular Weight: 383.369806 Pantoprazole Systematic (IUPAC)...
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