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Aldoxorubicin…CytRx is pouring money into R&D of cancer-fighting drugs
Aldoxorubicin, DOXO-EMCH...
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Telmapitant……Tachykinin NK1 Antagonists
Telmapitant TELMAPITANT; Telmapitant (USAN); Telmapitant [USAN]; 552292-58-7; HJ5FE4153B; D10391...
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Japan Proposes Influenza Drug To Treat Ebola… Pharmaceuticals: Country says...
The Japanese government said this week that it is prepared to make an influenza drug that is not approved for the treatment of Ebola available to West African countries hard-hit by the deadly virus....
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AMBROXOL
Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Mucobrox, Mucol, Lasolvan,...
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Levonadifloxacin arginine salt, WCK 771
STEREOCENTERS SHOWN Levonadifloxacin arginine salt, WCK 771 S-(−)-9-Fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic Acid l-Arginine Salt...
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Idasanutlin (RG-7388)…….for the oral treatment of cancer, including solid...
Idasanutlin(RG-7388) cas 1229705-06-9 4-{ [(2R,3S,4R,5S)-4-(4-Chloro-2-fluoro-phenyl)-3-(3-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2- dimethyl-prop yl)-pyrrolidine-2-carbonyl] -amino...
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Japanese researchers develop new 30-minute method to detect Ebola virus
Researchers from the Nagasaki University in Japan have developed a new method to detect the presence of Ebola virus in 30 minutes. The new method is claimed to allow doctors to rapidly diagnose the...
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Drug development, approval, manufacturing, and post-marketing…..Japan’s...
Drug development, approval, manufacturing, and post-marketing Development of a new drug involves a complicated process that requires a lot of time and enormous amounts of funding. In order to create...
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Lifitegrast, SAR 1118….effective inhibitor of LFA-1 interactions with ICAM-1
Lifitegrast, SAR 1118 SAR-1118-023 CAS 1025967-78-5 L-Phenylalanine, N-[[2-(6-benzofuranylcarbonyl)-5,7-dichloro-1,2,3,4-tetrahydro-6-isoquinolinyl]carbonyl]-3-(methylsulfonyl)-...
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AMRI Introduces Protein Expression & Purification Solutions
A MESSAGE FROM MICHAEL A. LUTHER, SENIOR VICE PRESIDENT DISCOVERY AND DEVELOPMENT Dear Anthony,As a company with a deep history of discovery innovation, Albany Molecular Research Inc. (AMRI)...
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21′α-Cyanoanhydrovinblastine
Some derivatives ) are known as being intermediates in the preparation of anti-tumor medicaments such as vinblastine, vincristine and vinorelbine. R=CH3, vinblastine R=CHO, vincristine n=2,...
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Acebutolol……..For the management of hypertension and ventricular premature...
Acebutolol N-(3-Acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl)butanamide 3′-acetyl-4′-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide (±)-acebutolol Acetobutolol; Sectral; Prent; Neptal;...
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FDA approves Keytruda for advanced melanoma, First PD-1 blocking drug to...
September 4, 2014 FDA Release The U.S. Food and Drug Administration today granted accelerated approval to Keytruda (pembrolizumab) for treatment of patients with advanced or unresectable melanoma who...
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Rhodium Expands Collection Of Metal-Based Anticancer Agents
ACS Meeting News: New class of inorganic reagents may provide less toxic and more versatile alternatives to popular platinum-based drug More than half of all cancer patients receive a platinum-based...
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New Route to Paricalcitol
Synthesis offers potential routes to analogues of vitamin-D-based drug Paricalcitol, an A-ring-modified 19-nor analogue of 1α,25-dihydroxyvitamin D2, is currently used for the treatment and prevention...
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Continuous flow-processing of organometallic reagents using an advanced...
Continuous flow-processing of organometallic reagents using an advanced peristaltic pumping system and the telescoped flow synthesis of (E/Z)-tamoxifen P.R.D. Murray, D.L. Browne, J.C. Pastre, C....
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Synthesis of (-)-hennoxazole A: integrating batch and flow chemistry methods
Synthesis of (-)-hennoxazole A: integrating batch and flow chemistry methods A. Fernández, Z.G. Levine, M. Baumann, S. Sulzer-Mossé, C. Sparr, S. Schläger, A. Metzger, I.R. Baxendale, S.V....
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The flow synthesis of heterocycles for natural products and medicinal...
The flow synthesis of heterocycles for natural products and medicinal chemistry applications http://link.springer.com/article/10.1007%2Fs11030-010-9282-1 M. Baumann, I.R. Baxendale, S.V. Ley, Mol....
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Bitter Fruit Bears Protein That Can Act Like Insulin
INSULIN LITE Researchers identified a protein (sphere representation) that binds to and activates the insulin receptor (ribbon structure), though it’s less potent at turning on the receptor than...
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An automated flow-based synthesis of imatinib: the API of gleevec
An automated flow-based synthesis of imatinib: the API of gleevec M.D. Hopkin, I.R. Baxendale, S.V. Ley, J.C.S. Chem. Commun.2010, 46, 2450-2452....
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