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Continuous flow chemistry: a discovery tool for new chemical reactivity patterns
Continuous flow chemistry: a discovery tool for new chemical reactivity patterns Jan Hartwig,a Jan B. Metternich,b Nikzad Nikbin,b Andreas Kirschninga and Steven V. Ley*b *Corresponding...
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A smarter way to find new drugs
End to end solutions Big Data push to research In Green / shutterstock.com The pharma sector needs to embrace emerging technologies like Big Data analytics and cloud computing What is the secret...
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A human recombinant monoclonal antibody to cocaine: Preparation,...
A human recombinant monoclonal antibody to cocaine: Preparation, characterization and behavioral studies CLICK…….http://www.sciencedirect.com/science/article/pii/S0960894X1400866X Bioorganic &...
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I did not run away from a NaCN Exotherm
DELTAMETHRIN DID NOT RUN AWAY FROM NACN ie sodium cyanide EXOTHERM ALMOST VIRTUAL ACCIDENT AT RPG LIFESCIENCES (SEARLE) PANOLI GUJARAT INDIA 1999-2000 DELTAMETHRIN PROJECT, 1999-2000 Panoli Gujarat...
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Cancer, Chemistry, and the Cell: Molecules that Interact with the Neurotensin...
Cancer, Chemistry, and the Cell: Molecules that Interact with the Neurotensin Receptors R.M. Myers,* J.W. Shearman, M.O. Kitching, A. Ramos-Montoya, D.E. Neal, S.V. Ley, ACS Chem. Biol.2009, 4,...
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Welcome Scientific update to Pune, India 2-3 and 4-5 Dec 2014 for celebrating...
WEBSITE http://www.scientificupdate.co.uk/ SCIENTIFIC UPDATE HAS A REPUTATION FOR ITS HIGH QUALITY EVENTS, BOTH FOR THE SCIENTIFIC CONTENT AND ALSO FOR THE EFFICIENCY OF ITS ORGANISATION. KEEP YOUR...
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LANOCONAZOLE
Lanoconazole READ AT http://newdrugapprovals.org/2014/10/02/lanoconazole/ Latoconazole, Lanoconazole, TJN-318, NND-318, Astat, Nihon Nohyaku (Originator), Tsumura (Licensee) Synonym:...
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Direct Route To Natural Products, Drug Discovery: Technique zeroes in on...
SETTING PRIORITIES A real-time PCR technique saves time and energy in natural product drug discovery by screening microbes for those that biosynthesize desired compound families. Credit: J. Nat. Prod....
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QUALITY BY DESIGN (QBD) IN API
Qbd by Anthony Melvin Crasto for API from ANTHONY MELVIN CRASTO Ph.D worlddrugtracker
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Dr. Rafael “Rafi” Boritzer’s “Bioinfomedical” scaling new heights
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Green chemistry makes ‘cents’ for cost-focused API firms says expert
Green chemistry makes ‘cents’ for cost-focused API firms says expert By Gareth MacDonald+, 07-Oct-2014 Making drugs generates a huge amount of waste but industry is showing signs of cleaning up its...
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Highly potent APIs: can lean manufacturing ever be safe?
Highly potent APIs: can lean manufacturing ever be safe? By Fiona Barry +, 09-Oct-2014 The phrase “lean manufacturing” conjures up job cuts and not much more for many people, but managers can use the...
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PRISMANE
PRISMANE Prismane is a polycyclic hydrocarbon with the formula C6H6. It is an isomer of benzene, specifically a valence isomer. Prismane is far less stable than benzene. The carbon (and hydrogen)...
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DIISOPROPYLAMINE SPECTROSCOPY TAUGHT BY MOM, AUNT
MOM DIISOPROPYLAMINE C6H15N MW 101 the degree of unsaturation: the answer is 0. The molecule has no double bonds or rings. IR Spectrum Since the molecule has a nitrogen, look for a band in the...
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The continuous flow synthesis of carboxylic acids using CO2 in a tube-in-tube...
The continuous flow synthesis of carboxylic acids using CO2 in a tube-in-tube gas permeable membrane reactor A. Polyzos, M. O’Brien, T. Pugaard-Petersen, I.R. Baxendale, S.V. Ley, Angew. Chem. Int....
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Deltamethrin an agrochemical can help control Malaria
Deltamethrin Deltamethrin is a pyrethroid ester insecticide. : AC1O570W; NRDC-161; 52918-63-5; FMC-45498; ZINC01532093; RU 23938; UNII-26515THS0L component OWZREIFADZCYQD-BJLQDIEVSA-N CAS :...
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[3 + 2] Cycloaddition of Acetylenes with Azides to give 1,4-Disubstituted...
[3 + 2] Cycloaddition of Acetylenes with Azides to give 1,4-Disubstituted 1,2,3- Triazoles in a Modular Flow Reactor C.D. Smith, I.R. Baxendale, S. Lanners, J.J. Hayward, S.C. Smith and S.V. Ley,...
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Tagged Phosphine Reagents to Assist Reaction Work-up by Phase-Switched...
The use of three orthogonally tagged phosphine reagents to assist chemical work-up via phase-switch scavenging in conjunction with a modular flow reactor is described. These techniques (acidic,...
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Continuous flow chemistry: a discovery tool for new chemical reactivity patterns
Continuous flow chemistry: a discovery tool for new chemical reactivity patterns J. Hartwig, J.B. Metternich, N. Nikbin, A. Kirschning, S.V. Ley, Org. Bio. Chem. 2014, 12, 3611...
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Mild and selective heterogeneous catalytic hydration of nitriles to amides by...
A sustainable flow chemistry process for the hydration of nitriles, whereby an aqueous solution of the nitrile is passed through a column containing commercially available amorphous manganese dioxide,...
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