3,5-Dibromo-N-(4,6-difluorobenzo[d]thiazol-2-yl)thiophene-2-carboxamide...
3,5-Dibromo-N-(4,6-difluorobenzo[d]thiazol-2-yl)thiophene-2-carboxamide New and novel anti-norovirus agents There is an urgent need for structurally novel anti-norovirus agents. In this study, we...
View ArticlePreparation and Evaluation of Solid Dispersion Tablets by a Simple and...
The aim of this study was to prepare and evaluate solid dispersion tablets containing a poorly water-soluble drug using porous calcium silicate (PCS) by a wet granulation method. Nifedipine (NIF)...
View ArticleA Novel Scale Up Model for Prediction of Pharmaceutical Film Coating Process...
In the pharmaceutical tablet film coating process, we clarified that a difference in exhaust air relative humidity can be used to detect differences in process parameters values, the relative humidity...
View ArticleSynthesis, Biological Evaluation and Validation Studies of Novel...
Procedure for the synthesized derivatives (1-3) Step 1: The synthesis of Intermediate-1 (2-imino-6-methyl-4- (substituted aldehyde)-N-phenyl-1,2,3,4-tetrahydropyrimidine-5- carboxamide): A mixture of...
View ArticleDr Anthony’s New Drug Approvals hits 13 lakh views in 212 countries
Dr Anthony’s New Drug Approvals hits 13 lakh views in 212 countries An Indian helping millions MAKING INDIANS FEEL PROUD LINK https://newdrugapprovals.org/ ////////blog, Dr Anthony , New Drug...
View ArticleWHO defines Requirements on Zones E and F
In May, the WHO published a draft guideline which describes the recommendations for ventilation systems used in the manufacture of non-sterile dosage forms. It also contains for the first time a...
View ArticlePonesimod
Ponesimod Phase III MW 460.97, C23 H25 Cl N2 O4 S A sphingosine-1-phosphate receptor 1 (S1P1) agonist potentially for the treatment of multiple sclerosis....
View ArticleGSK-2879552
GSK-2879552 CAS 1401966-69-5 (ABS), 1401966-63-9(REL) C23 H28 N2 O2, 364.48 Benzoic acid, 4-[[4-[[[(1R,2S)-2-phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]-...
View ArticleGSK-2881078
GSK-2881078 (R)-1-[1-(Methylsulfonyl)propan-2-yl]-4-(trifluoromethyl)-1H-indole-5-carbonitrile (R)-1 -(1-(methylsulfonyl)propan-2-yl)-4-(trifluoromethyl)indoline-5-carbonitrile Phase I A selective...
View ArticleMaralixibat Chloride, ماراليكسيبات كلوريد , 氯马昔巴特 , Мараликсибата хлорид
Maralixibat chloride Maralixibat Chloride, ماراليكسيبات كلوريد , 氯马昔巴特 , Мараликсибата хлорид SHP625, Maralixibat chloride, Molecular Formula C40-H56-N3-O4-S.Cl, Molecular Weight, 710.4184...
View ArticleAMG 900, An aurora kinase (ARK) inhibitor potentially for the treatment of...
AMG-900 N-(4-((3-(2-aminopyrimidin-4-yl)pyridin-2-yl)oxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine....
View ArticleGSK 1070916 For Advanced solid tumor
GSK 1070916 NMI-900 , GSK-1070916, GSK-1070916A 4-[3-(4-N,N-Dimethylcarbamylaminophenyl)-1-ethyl-1H-pyrazol-4-yl]-2-[3-(dimethylaminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridine...
View ArticleAmneal Pharma’s, 4,5-Dihydro-1H-pyrazolo[3,4-d]pyrimidine containing...
Cas 1580464-40-9 MW458.97, C24 H19 Cl N6 S, 1H-Pyrazolo[3,4-d]pyrimidin-6-amine, 4-(4-chlorophenyl)-4,7-dihydro-3-methyl-1-(10H-phenothiazin-2-yl)-...
View ArticleFinal WHO Guidance Document on Good Data and Record Management Practices
The WHO has just released the the final version of the important guideline “Good Data and Record Management Practices“....
View ArticleRevision of the general Chapter on Pharmaceutical Water in the US Pharmacopoeia
The 2nd supplement of USP39 NF34 comprises the revised version of the chapter on pharmaceutical water of the US Pharmacopoeia <1231> Water for pharmaceutical purposes....
View ArticleRecilisib Sodium, EX-RAD
Recilisib Sodium Phase I C16H12ClNaO4S Molecular Weight: 358.771849 g/mol A protein kinase inhibitor potentially for the treatment of acute radiation syndrome....
View ArticleTherapeutic Effect of Amaranthus hybridus on Diabetic Nephropathy
Diabetes Nephropathy, a chronic metabolic complication of diabetes mellitus, is characterized by elevated levels of serum glucose,creatinine, urea and uric acid in addition to abnormal...
View ArticleSynthesis and Low Temperature Spectroscopic Observation of...
1,3,5-Trioxane-2,4,6-trione (cyclic trimer of CO2) is the product of a four-step synthesis: chlorination of isobutyraldehyde; cyclotrimerization of 2-chloro-2-methylpropanal; dehydochlorination of...
View ArticleNovartis, Torrent drug for diabetes, NVP-LBX192, LBX-192
(R)-3-Cyclopentyl-N-(5-methoxy-thiazolo[5,4-b]pyridin-2-yl)-2-[4-(4-methyl-piperazine-1-sulfonyl)-phenyl]-propionamide...
View Article