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Self-optimisation of the final stage in the synthesis of EGFR kinase...
React. Chem. Eng., 2016, Advance Article DOI: 10.1039/C6RE00059B, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Nicholas Holmes, Geoffrey...
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Intensified biocatalytic production of enantiomerically pure...
Catal. Sci. Technol., 2016, Advance Article DOI: 10.1039/C6CY00855K, Communication Nicholas J. Weise, Syed T. Ahmed, Fabio Parmeggiani, Elina Siirola, Ahir Pushpanath, Ursula Schell, Nicholas J....
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Mechanisms and reactivity differences of proline-mediated catalysis in water...
Catal. Sci. Technol., 2016, 6,3378-3385 DOI: 10.1039/C6CY00033A, Paper Gang Yang, Lijun Zhou Several key issues regarding the mechanisms of proline catalysis are unravelled by first-principles...
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Activated nanostructured bimetallic catalysts for C-C coupling reactions:...
Catal. Sci. Technol., 2016, 6,3341-3361 DOI: 10.1039/C5CY02225H, Minireview Rohit Kumar Rai, Deepika Tyagi, Kavita Gupta, Sanjay Kumar Singh This minireview highlights the recent progress made in the...
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Дапипразол Dapiprazole
Dapiprazole CAS 72822-12-9 HCL SALT 72822-13-0 5,6,7,8-Tetrahydro-3-(2-(4-(O-tolyl)-1-piperazinyl)ethyl)-S-triazolo(4,3-a)pyridine Dapiprazole (Rev-Eyes) is an alpha blocker. It is used to reverse...
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EDQM’s new Guideline on Electronic Submissions for CEP Applications
EDQM’s new Guideline on Electronic Submissions for CEP Applications As of today (June, 1st 2016), the EDQM doesn’t accept any CEP application in paper format. Read more here about the structure of...
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Results of a Survey on ICH Q3D “Elemental Impurities”
For most companies manufacturing APIs and pharmaceutical products, the implementation of ICH Q3D has a serious impact – as shown in a survey recently carried out by the ECA. Read more about the issues...
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Ladostigil
Ladostigil, TV-3,326 (N-propargyl-(3R) aminoindan-5yl)-ethyl methyl carbamate (3R)-3-(Prop-2-ynylamino)indan-5-yl ethyl(methyl)carbamate; R-CPAI Carbamic acid, ethylmethyl-,...
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Flow Chemistry Symposium & Workshop 16-17 June at IICT, Hyderabad, India
MESSAGE FROM VIJAY KIRPALANI A 2-day FLOW CHEMISTRY Symposium + Workshop has been organized on 16-17 June 2016 at IICT Hyderabad, India by Flow Chemistry Society – India Chapter (in collaboration...
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Obeticholic acid
Obeticholic acid Obeticholic acid; 6-ECDCA; INT-747; 459789-99-2; 6-Ethylchenodeoxycholic acid; 6alpha-Ethyl-chenodeoxycholic acid;...
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Surface-Cross-Linked Micelles as Multifunctionalized Organic Nanoparticles...
Surfactant micelles are dynamic entities with a rapid exchange of monomers. By “clicking” tripropargylammonium-containing surfactants with diazide cross-linkers, we obtained surface-cross-linked...
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Concise Cu (I) Catalyzed Synthesis of Substituted Benzofurans via a Tandem...
A novel and convergent approach to tetrasubstituted benzofurans was developed from ortho-bromo aryl fluorides and keto-amides via one-pot SNAr displacement and subsequent Cu(I) catalyzed C–O coupling...
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Cs2CO3 as a source of carbonyl and ethereal oxygen in a Cu-catalysed cascade...
Org. Biomol. Chem., 2016, Advance Article DOI: 10.1039/C6OB01029F, Communication Wajid Ali, Anju Modi, Ahalya Behera, Prakash Ranjan Mohanta, Bhisma K. Patel Simultaneous construction of C-C, C-O, and...
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Asian International Continuous Flow Chemistry Summit/Chemtrix BV at...
Asian International Continuous Flow Chemistry Summit at CPhI-China 2016 weblink…….http://www.chemtrix.com/news/65/Asian-International-Continuous-Flow-Chemistry-Summit CPhI – China on 22nd June 2016...
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JNJ-54257099
JNJ-54257099, 1-((2R,4aR,6R,7R,7aR)-2-Isopropoxy-2-oxidodihydro-4H,6H-spiro[furo[3,2-d][1,3,2]dioxaphosphinine-7,2′-oxetan]-6-yl)pyrimidine-2,4(1H,3H)-dione MW 374.28, C14 H19 N2 O8 P CAS...
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AM 2394
AM 2394 1-(6′-(2-hydroxy-2-methylpropoxy)-4-((5-methylpyridin-3-yl)oxy)-[3,3′-bipyridin]-6-yl)-3-methylurea Urea,...
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Cyclopropylacetyl-(R)-carnitine
NMR Data of Cyclopropylacetyl-(R)-carnitine (4) Position 1H-NMR (300 MHz, D2O) HOD=4.79 13C-NMR (75 MHz, D2O) DSSa)=−2.04 HMBC correlation 1 — 177.1 C2-Ha, Hb 2 a: 2.49 (1H, dd, J=8.0, 16.0 Hz) 40.9...
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Preparation of Fine Particles with Improved Solubility Using a Complex...
Fig. 1. Schematic Representation of a Complex Fluidized-Bed Granulator 1: Exhaust air, 2: bag filter, 3: partition tube, 4: impeller, 5: rotor disc, 6: inlet air, 7: screen, 8: spray nozzle....
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A Process Monitoring Solution that is Flexible and Scalable
A Process Monitoring Solution that is Flexible and Scalable The Unscrambler® X Process Pulse II can be utilised in all levels of an organisation, providing solutions to a variety of challenges using...
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Predicting the Occurrence of Sticking during Tablet Production by Shear...
A larger SI indicates a greater likelihood that sticking will occur. Defining SI for Assessing Adhesion of Powder to the Punch One cause of sticking is that when a powder is being compacted, the...
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